1499
| Years: 1496 1497 1498 - 1499 - 1500 1501 1502 | |
| Decades: 1460s 1470s 1480s - 1490s - 1500s 1510s 1520s | |
| Centuries: 14th century - 15th century - 16th century | |
Events
- July 22 - Battle of Dornach - The Swiss decisively defeat the Imperial army of Emperor Maximilian I.
- July 28 - First Battle of Lepanto - The Turkish navy wins a decisive victory over the Venetians.
- September 22 - Treaty of Basel. Maximilian is forced to grant the Swiss de facto independence.
- November 23 - Pretender to the throne Perkin Warbeck is hanged for reportedly attempting to escape from the Tower of London. In 1497 he invaded England claiming to be the lost son of King Edward IV of England.
- November 28 - Edward, Earl of Warwick is executed for reportedly attempting to escape from the Tower of London. He was the last male member of the House of York.
- The French under Louis XII seize Milan, driving out Duke Ludovico Sforza.
Births
- January 29 - Katharina von Bora, German Catholic nun who was an early convert to Protestantism (died 1552)
- February 10 - Thomas Platter, humanist scholar and writer (died 1582)
- February 21 - Edmund Tudor, Duke of Somerset, sixth child of Henry VII of England (died 1500)
- March 31 - Pope Pius IV (died 1565)
- September 3 - Diane de Poitiers, French mistress of Henry II of France (died 1566)
- October 14 - Queen Claude of France (died 1524)
- Hans Asper, Swiss painter (died 1571)
- Juan Rodríguez Cabrillo, Portuguese explorer (died 1543)
- Michael Coxcie, Flemish painter (died 1592)
- Jan Laski, Polish Protestant evangelical reformer (died 1560)
- Laurentius Petri, Archbishop of Uppsala (died 1573)
- Giulio Romano, Italian painter (died 1546)
- Bernardino de Sahagún, Franciscan missionary to the Aztec (Náhua) people of Mexico (died 1590)
- Niccolo Fontana Tartaglia, mathematician (died 1557)
Deaths
- October 1 - Marsilio Ficino, Italian philosopher (born 1433)
- November 23 - Perkin Warbeck, pretender to the English throne (born 1474)
- November 28 - Edward, Earl of Warwick, last male member of the English House of York (born 1475)
- Alessio Baldovinetti, Florentine painter (born 1427)
- John Cabot, Italian explorer (born 1450)
- Johann Cicero, Elector of Brandenburg (born 1455)
- Rennyo, one of the leaders of the Jodo Shinshu sect (born 1415)