165
| Years: 161 162 163 164 - 165 - 166 167 168 169 | |
| Decades: 130s 140s 150s - 160s - 170s 180s 190s | |
| Centuries: 1st century - 2nd century - 3rd century | |
Events
- A pandemic known as the Antonine Plague breaks out in Rome after the Roman army returns from Parthia.
- Legio II Italica is levied by Roman emperor Marcus Aurelius.
Births
- Macrinus, Roman emperor (approximate date)
Deaths
- Justin Martyr, early apologist for Christianity
- Claudius Ptolemaeus, Greek astronomer (approximate date)