Acyloin condensation

In chemistry, the acyloin condensation is a reductive coupling of two carboxylic esters using metallic sodium to give an α-hydroxyketone, also known as an acyloin.

The reaction is most successful when R is aliphatic and inert, high-boiling solvents such as benzene and toluene are used.

References

• Bouveault, L.; Loquin, R. Compt. Rend. 1905, 140, 1593.
• Finley, K. T. Chem. Rev. 1964, 64, 573.

See also

• Benzoin condensation
• Bouveault-Blanc reduction

See also: Acyloin condensation, Aliphatic, Benzene, Benzoin condensation, Chemical reaction, Chemistry, Ester, Redox, Sodium